The hapmap project : Nature

Tag SNP selection for Finnish individuals based on the CEPH Utah HapMap database.

The pattern and nature of linkage disequilibrium in the human genome is being studied and catalogued as part of the International HapMap Project [:2003 Nature 426:789-796]. A key goal of the HapMap Project is to enable identification of tag single nucleotide polymorphisms (SNPs) that capture a substantial portion of common human genetic variability while requiring only a small fraction of SNPs ...

A comparison of cataloged variation between International HapMap Consortium and 1000 Genomes Project data

BACKGROUND Since publication of the human genome in 2003, geneticists have been interested in risk variant associations to resolve the etiology of traits and complex diseases. The International HapMap Consortium undertook an effort to catalog all common variation across the genome (variants with a minor allele frequency (MAF) of at least 5% in one or more ethnic groups). HapMap along with advan...

Genetic variation and the HapMap Project I

Challenges to public engagement in science and technology in Japan: experiences in the HapMap Project

Public engagement in science and technology has grown in importance as developments in science and technology make increasingly significant impacts on people’s lives. Now, efforts to engage publics in social decision-making or consensusbuilding regarding science and technology involve participation, learning or deliberation opportunities, as well as interactive or coproductive efforts among var...

Perspectives on Human Genetic Variation from the HapMap Project

The completion of the International HapMap Project marks the start of a new phase in human genetics. The aim of the project was to provide a resource that facilitates the design of efficient genome-wide association studies, through characterising patterns of genetic variation and linkage disequilibrium in a sample of 270 individuals across four geographical populations. In total, over one milli...